Hypertension epidemiology in India: meta-analysis of 50 year prevalence rates and blood pressure trends.

Hypertension epidemiology in India: meta-analysis of 50 year prevalence rates and blood pressure trends.
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印度高血压流行病学:50 年患病率和血压趋势的荟萃分析。

DOI:
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发表时间:
1996
影响因子:
2.7
通讯作者:
Gupta Vp
Gupta Vp
中科院分区:
医学4区
文献类型:
--
作者:
R. Gupta;al;Gupta Vp

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最近对印度人的研究表明,高血压的发病率很高。为了确定高血压患病率的变化趋势,平均血压(BP)水平,并研究城市和农村的差异,我们对所有可用的印度研究进行了荟萃分析。第一个这样的研究是由Chopra在1942年报道的。从那时起,在印度的城市和农村地区进行了许多研究(n = 33)。在城市人群中,Dotto(1949)、Dubey(1954)和Sathe(1959)的早期研究显示,加尔各答、坎普尔和孟买人群的高血压患病率分别为1.24 +/-0.2%、4.24 +/-0.4%和3.03 +/- 0.3%。自1959年以来的研究使用世界卫生组织(WHO)指南,并显示高血压患病率呈上升趋势。卢迪亚纳(1985年)和斋浦尔(1995年)最近的研究表明,流行率分别为14.08 +/-1.1%和10.99 +/- 0.7%。城市地区研究的趋势分析(n = 10)显示高血压患病率显著增加(Mantel-Haenzel χ 2 = 5.99,P = 0.014)。农村地区的研究(n = 14)也显示高血压患病率显著增加(Mantel-Haenzel χ 2 = 5.93,P = 0.014),尽管上升幅度不如城市人群(r值,城市= 0.70,农村= 0.67)。采用平均收缩压(S)和平均舒张压(D)分析了1959 ~ 1995年40-49岁城市男性平均血压水平的变化。收缩压显著升高(r = 0.95,P < 0.001),舒张压无显著升高(r = 0.43,P > 0.2)。它的结论是,在印度高血压正在成为一个主要的健康问题,所以在城市比在农村科目。患病率的增加与平均SBP的升高有关。
Recent studies among Indians have shown a high prevalence of hypertension. To determine changing trends in hypertension prevalence, in mean blood pressure (BP) levels and to study urban and rural differences we performed meta-analysis of all available Indian studies. The first such study was reported by Chopra in 1942. Since then many studies (n = 33) in urban and rural areas of India have been performed. In urban populations earlier studies of Dotto (1949), Dubey (1954) and Sathe (1959) showed prevalence of hypertension of 1.24 +/- 0.2, 4.24 +/- 0.4 and 3.03 +/- 0.3% in populations of Calcutta, Kanpur and Bombay respectively. Studies since 1959 used World Health Organisation (WHO) guidelines and have shown increasing trend in hypertension prevalence. Recent studies from Ludhiana (1985) and Jaipur (1995) show that prevalence is 14.08 +/- 1.1 and 10.99 +/- 0.7% respectively. Trend analysis in studies among urban areas (n = 10) shows a significant increase in hypertension prevalence (Mantel-Haenzel chi 2 = 5.99, P = 0.014). Studies in rural areas (n = 14) also show a significant increase in hypertension prevalence (Mantel-Haenzel chi 2 = 5.93, P = 0.014) although the rise is not as sharp as in urban populations (r value, urban = 0.70, rural = 0.67). Changes in mean BP levels were analysed by using mean systolic (S) and diastolic (D) BP in urban men aged 40-49 years from 1959-1995. For SBP there was a significant increase (r = 0.95, P < 0.001) and not with DBP (r = 0.43, P > 0.2). It is concluded that in India hypertension is emerging as a major health problem more so in urban than in rural subjects. The increasing prevalence is related to a rising mean SBP.