Rheumatologic manifestations of human parvovirus B19 infection in adults. Initial two-year clinical experience.
Rheumatologic manifestations of human parvovirus B19 infection in adults. Initial two-year clinical experience.
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成人人类细小病毒 B19 感染的风湿病表现。
DOI：
10.1002/art.1780330901
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发表时间：
1990
影响因子：
--
通讯作者：
Howard,EJ
中科院分区：
文献类型：
--
作者：
Naides,SJ;Scharosch,LL;Foto,F;Howard,EJ
在1987年和1988年期间，我们在爱荷华州大学医院和诊所的医学和流变学服务处确定了9名临床诊断为第五种疾病的成年人; 9人中有8人有关节受累的症状。另外12名抗细小病毒B19 IgM抗体血清学阳性的成人出现多关节痛/多关节炎。患者通常被发现是血清阴性的类风湿因子，没有发展结节或糜烂性疾病。许多慢性病患者符合类风湿性关节炎的诊断标准。多关节痛/多关节炎患者初次就诊时应考虑细小病毒B19感染的诊断。
During 1987 and 1988, we identified 9 adults at the Medical and Rheumatology Services of the University of Iowa Hospitals and Clinics who had a clinical diagnosis of fifth disease; 8 of the 9 had symptoms of joint involvement. Another 12 adults with serologic positivity for anti‐parvovirus B19 IgM antibody presented with polyarthralgia/polyarthritis. Patients were usually found to be seronegative for rheumatoid factor, and none developed nodules or erosive disease. Many patients with chronic disease met criteria for a diagnosis of rheumatoid arthritis. A diagnosis of parvovirus B19 infection should be considered during the initial visit of patients with polyarthralgia/polyarthritis.