West Nile virus surveillance and diagnostics: A Canadian perspective.
West Nile virus surveillance and diagnostics: A Canadian perspective.
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DOI：
10.1155/2003/575341
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发表时间：
2003-03
期刊：
影响因子：
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通讯作者：
M. Drebot;R. Lindsay;I. Barker;P. Buck;M. Fearon;Fiona Hunter;P. Sockett;H. Artsob
中科院分区：
文献类型：
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作者：
M. Drebot;R. Lindsay;I. Barker;P. Buck;M. Fearon;Fiona Hunter;P. Sockett;H. Artsob
自2000年以来，加拿大一直在实施一项监测方案，以检测西尼罗河病毒（WNV）在加拿大的存在。在监测人类疾病和进行病例调查时，血清学测定是最合适的。基因组扩增程序更常用于检测作为持续监测工作的一部分而收集的动物和蚊子标本。2001年夏末和秋季，西尼罗河病毒在安大略的12个卫生单位首次入侵该国。2002年5月中旬，安大略的鸟类监测记录了西尼罗河病毒的活动，随后该病毒在整个安大略扩散，并进入魁北克、马尼托巴、萨斯喀彻温和新斯科舍省。2002年，安大略和魁北克都记录了人间病例，发现了大约800至1000例可能、确诊和疑似病例。必须预测2003年西尼罗河病毒可能复发并进一步传播到加拿大其他地区，对公共卫生构成潜在风险。继续监测与西尼罗河病毒有关的人类疾病是必要的，2003年需要采取适当的疾病预防措施。
A surveillance program has been in place since 2000 to detect the presence of West Nile virus (WNV) in Canada. Serological assays are most appropriate when monitoring for human disease and undertaking case investigations. Genomic amplification procedures are more commonly used for testing animal and mosquito specimens collected as part of ongoing surveillance efforts. The incursion of WNV into this country was documented for the first time in 2001 when WNV was demonstrated in 12 Ontario health units during the late summer and fall. In 2002 WNV activity was documented by avian surveillance in Ontario by mid-May with subsequent expansion of the virus throughout Ontario and into Quebec, Manitoba, Saskatchewan and Nova Scotia. Human cases were recorded in both Ontario and Quebec in 2002 with approximately 800 to 1000 probable, confirmed and suspect cases detected. The possible recurrence and further spread of WNV to other parts of Canada in 2003 must be anticipated with potential risk to public health. The continued surveillance and monitoring for WNV-associated human illness is necessary and appropriate disease prevention measures need to be in place in 2003.