Trends in survival for both histologic types of esophageal cancer in US surveillance, epidemiology and end results areas
Trends in survival for both histologic types of esophageal cancer in US surveillance, epidemiology and end results areas
复制标题
DOI：
10.1002/ijc.11029
复制
发表时间：
2003-05-20
影响因子：
6.4
通讯作者：
Polednak, AP
中科院分区：
文献类型：
--
作者：
Polednak, AP
对瑞典1961-1996年诊断的食管癌患者的时间趋势分析显示，相对生存率（RSRs）有所改善，但诊断阶段或癌症定向治疗的数据不可用。1本报告考虑了美国食管癌患者的组织学RR的时间变化。国家癌症研究所的高质量癌症登记处的监测，流行病学和最终结果（SEER）计划，成立于1973年，被认为是整个美国的普遍代表。2数据来自9个SEER地区（康涅狄格州、密歇根州底特律、夏威夷、爱荷华州、新墨西哥州、加利福尼亚州旧金山-奥克兰、华盛顿州西雅图、犹他州以及自1975年以来的佐治亚州亚特兰大）。将食管癌作为第一个或唯一可报告的癌症的患者确定，排除仅通过死亡证明或尸检确定的患者。（按年龄、性别和种族），1975-1979年、1980-1984年、1985-1989年诊断后1年、3年和5年的3个RSR，1990-1994年和1995-1998年获得了食管鳞状细胞癌和腺癌（由ICDO-2形态学代码定义）。4估计RSRs的置信限为SE的两倍（p 0.05）。3按组织学分组的RSRs未常规纳入SEER报告，2一份关于组织学的SEER专著仅纳入了1986年之前诊断的癌症数据。4，5另一项SEER研究仅限于食管腺癌，显示20世纪80年代与早些年相比，RSRs略有增加。6
An analysis of temporal trends for esophageal cancer patients diagnosed in 1961–1996 in Sweden showed improvement in relative survival rates (RSRs), but data were not available on stage at diagnosis or on cancer-directed treatment. 1 The present report considers temporal changes in RSRs by histology for esophageal cancer patients in the United States. The National Cancer Institute’s Surveillance, Epidemiology and End Results (SEER) program of high-quality cancer registries, established in 1973 and regarded as generally representative of the entire United States. 2 Data were obtained for the 9 SEER areas (Connecticut; Detroit, MI; Hawaii; Iowa; New Mexico; San Francisco–Oakland, CA; Seattle, WA; Utah; and, since 1975, Atlanta, GA). Patients with esophageal cancer as the first or only reportable cancer were identified, excluding those ascertained only by death certificate or autopsy.Using a computer program that includes mortality rates for the general US population (by age, sex and race), 3 RSRs at 1, 3 and 5 years after diagnosis in 1975–1979, 1980–1984, 1985–1989, 1990–1994 and 1995–1998 were obtained for squamous cell carcinoma and adenocarcinoma of the esophagus (defined by ICDO-2 morphology codes). 4 Confidence limits on RSRs were estimated as twice the SE (p 0.05). 3 RSRs by histologic group are not routinely included in SEER reports, 2 and a SEER monograph on histology included data for cancers diagnosed only through 1986. 4, 5 Another SEER study was limited to esophageal adenocarcinoma, showing slight increases in RSRs in the 1980s vs. earlier years. 6