Prevalence of allergic rhinitis in patients with attention-deficit/hyperactivity disorder: a population-based study
Prevalence of allergic rhinitis in patients with attention-deficit/hyperactivity disorder: a population-based study
复制标题
DOI：
10.1007/s00787-012-0369-3
复制
发表时间：
2013-05-01
影响因子：
6.4
通讯作者：
Lan, Tsuo-Hung
中科院分区：
文献类型：
--
作者：
Chou, Po-Han;Lin, Chih-Chien;Lan, Tsuo-Hung
过敏性鼻炎（AR）在儿童中很常见。 AR 的典型症状可能导致白天注意力不集中、烦躁和多动，这些也是 ADHD 的组成部分。先前的研究中关于 ADHD 和 AR 之间的关系存在相互矛盾的数据。本研究的目的是调查台湾 ADHD 患者 AR 的患病率和风险。我们利用台湾的国民健康保险研究数据库进行了一项横断面研究。研究对象包括 2005 年因 ADHD 接受精神科护理的 469 名患者和普通人群 (n = 220,599)。通过chi（2）检验检查一般人群和ADHD组的年龄、性别、居住地区以及过敏性疾病的分布。采用多因素logistic回归模型分析AR的危险因素。 ADHD组和普通人群中AR的患病率分别为28.4%和15.2%。 ADHD 组的哮喘患病率为 9.6%，普通人群的哮喘患病率为 6.4%。 ADHD 组中 AR（p < 0.001）和哮喘（p = 0.008）的患病率均显着高于一般人群。多因素Logistic回归分析显示，ADHD患者的AR发生率高于一般人群（OR = 1.83；95% CI = 1.48-2.27；p < 0.0001），且哮喘与AR密切相关（OR = 9.28；95% CI = 8.95-9.63；p < 0.0001）。我们的数据显示 ADHD 患者 AR 发生率增加。因此，精神科医生在治疗ADHD患者时应更加意识到AR的合并症。
Allergic rhinitis (AR) is common in children. Characteristic symptoms of AR may result in daytime inattention, irritability, and hyperactivity, which are also components of ADHD. Conflicting data in previous studies exist regarding the relationship between ADHD and AR. The aim of this study was to examine the prevalence and risk of AR in ADHD patients in Taiwan. We conducted a cross-sectional study using the National Health Insurance Research Database in Taiwan. The study subjects included 469 patients who received psychiatric care for ADHD in 2005 and the general population (n = 220,599). Distributions of age, gender, and living areas as well as allergic diseases in the general population and in the ADHD group were examined by chi (2) tests. Multivariate logistic regression models were used to analyze the risk factors of AR. The prevalence of AR in ADHD group and the general population was 28.4 and 15.2 %, respectively. The prevalence of asthma was 9.6 % in ADHD group and 6.4 % in the general population. Both the prevalence of AR (p < 0.001) and asthma (p = 0.008) was significantly higher in ADHD group than the general population. The multivariate logistic regression analysis showed that ADHD patients had an increased rate of AR than general population (OR = 1.83; 95 % CI = 1.48-2.27; p < 0.0001), and asthma was strongly associated with AR (OR = 9.28; 95 % CI = 8.95-9.63; p < 0.0001). Our data showed that ADHD patients had an increased rate of AR. Therefore, psychiatrists should be more aware of the comorbidity of AR when treating ADHD patients.