Differences in motor cortical representations of kinematic variables between action observation and action execution and implications for brain-machine interfaces.
Differences in motor cortical representations of kinematic variables between action observation and action execution and implications for brain-machine interfaces.
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动作观察和动作执行之间运动学变量的运动皮质表示的差异以及对脑机接口的影响。
DOI：
10.1109/embc.2014.6943845
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发表时间：
2014
期刊：
影响因子：
--
通讯作者：
Hatsopoulos,NicholasG
中科院分区：
文献类型：
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作者：
Willett,FrancisR;Suminski,AaronJ;Fagg,AndrewH;Hatsopoulos,NicholasG
观察正在执行的动作和执行相同的动作会导致初级运动皮层（MI）出现类似的神经活动模式。以前的工作已经表明，在动作观察（AO）过程中诱发的神经活动是信息的运动学和肌肉激活模式的动作正在执行，虽然在动作观察过程中记录的神经活动包含的信息比在动作执行（AE）过程中记录的活动少。在这项研究中，我们扩展这些结果通过比较表示不同的运动学变量在MI单/多单元活动之间AO和AE条件在三只恒河猴。我们表明，表示的加速度比AO中的位置和速度的下降更显着（人口解码性能的加速度下降更陡峭，和更少的神经元AO编码加速度显着相比，AE）。我们讨论了这些结果的相关性，脑机接口，利用神经活动在AO初始化神经活动和电机命令之间的映射函数。
Observing an action being performed and executing the same action cause similar patterns of neural activity to emerge in the primary motor cortex (MI). Previous work has shown that the neural activity evoked during action observation (AO) is informative as to both the kinematics and muscle activation patterns of the action being performed, although the neural activity recorded during action observation contains less information than the activity recorded during action execution (AE). In this study, we extend these results by comparing the representation of different kinematic variables in MI single /multi unit activity between AO and AE conditions in three rhesus macaques. We show that the representation of acceleration decreases more significantly than that of position and velocity in AO (population decoding performance for acceleration decreases more steeply, and fewer neurons in AO encode acceleration significantly as compared to AE). We discuss the relevance of these results to brain-machine interfaces that make use of neural activity during AO to initialize a mapping function between neural activity and motor commands.