Microcystin-LR disturbs testicular development of giant freshwater prawn Macrobrachium rosenbergii
Microcystin-LR disturbs testicular development of giant freshwater prawn Macrobrachium rosenbergii
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DOI：
10.1016/j.chemosphere.2019.01.146
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发表时间：
2019
期刊：
影响因子：
8.8
通讯作者：
Wenzhi Wei
中科院分区：
文献类型：
--
作者：
Yingying Zhang;Hang Zhuang;Hui Yang;Wen Xue;Liufu Wang;Wenzhi Wei
Microcystins (MCs) are produced by cyanobacterial blooms and known for their hepatotoxicity. They could cause serious damage to the reproduction of higher vertebrate mice and fish. However, few studies have focused on the reproductive toxicity of MCs to invertebrates. Giant freshwater prawnMacrobrachium rosenbergiiare highly cultivated in China. During their breeding process,M. rosenbergiiare often infested by cyanobacteria blooms. In the present study, to investigate the toxic effect of MCs on the testicular development ofM. rosenbergii. MaleM. rosenbergiiwere exposed to environmental relevant concentration of MC-LR for 1, 2 and 3 weeks. Results showed that MC-LR enteredM. rosenbergiitestis, down-regulated hemolymph testosterone (T) levels, and damaged testicular germ cells, mitochondria and cell junctions, and inhibited testicular development. Moreover, MC-LR could significantly induce the expression of gonadal development related genes in testis and eyestalk). The present results indicate that MC-LR can disrupt the testicular development ofM. rosenbergiiby affecting T levels and gonadal development related genes in the testis and eyestalk.
