SKELETAL-MUSCLE DENSITY - EFFECTS OF OBESITY AND NON-INSULIN-DEPENDENT DIABETES-MELLITUS
SKELETAL-MUSCLE DENSITY - EFFECTS OF OBESITY AND NON-INSULIN-DEPENDENT DIABETES-MELLITUS
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DOI：
10.1093/ajcn/54.3.509
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发表时间：
1991-09-01
影响因子：
7.1
通讯作者：
JANOSKY, J
中科院分区：
文献类型：
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作者：
KELLEY, DE;SLASKY, BS;JANOSKY, J
肥胖与瘦肉质量增加有关，但其对瘦肉组织密度的影响尚不清楚。 为了研究肥胖和非胰岛素依赖型糖尿病 (NIDDM) 对瘦组织成分和密度的影响，我们对 20 名不同体重的男性进行了大腿中部的横截面计算机断层扫描 (CT) 扫描。 肥胖与大腿脂肪（r = 0.75）和瘦肉组织体积（r = 0.52）的增加以及瘦肉组织密度的降低（r = 0.73）相关。 肥胖者瘦组织的增加是由于非脂肪组织成分的密度低于肌肉的正常范围，NIDDM 加剧了这一效应，而正常密度的肌肉体积则没有变化。
Obesity is associated with increased lean mass but its effects on lean-tissue density are less clear. To examine the effects of obesity and non-insulin-dependent diabetes mellitus (NIDDM) on lean-tissue composition and density, cross-sectional computed tomography (CT) scans of the midthigh were obtained in 20 men of various weights. Obesity was associated with increases in thigh-adipose (r = 0.75) and lean-tissue volumes (r = 0.52) and with reduced density of lean tissue (r = 0.73). The increased lean tissue in obesity was due to a nonadipose tissue component with a density below the normal range of muscle, an effect compounded by NIDDM, whereas normal-density muscle volume was unchanged.