Burden of Uterine Fibroids: An African Perspective, A Call for Action and Opportunity for Intervention.
Burden of Uterine Fibroids: An African Perspective, A Call for Action and Opportunity for Intervention.
复制标题
DOI：
10.18314/cogo.v2i1.1701
复制
发表时间：
2019-01-01
期刊：
影响因子：
--
通讯作者：
Al-Hendy, A
中科院分区：
文献类型：
--
作者：
Igboeli, P;Walker, W;Al-Hendy, A
黑人妇女携带子宫肌瘤的负担，（又名子宫平滑肌瘤），在一个更高的比率比他们的种族同行。因此，提高人们的认识并找到解决困扰撒哈拉以南非洲地区的地方性问题的方法不仅对该地区本身至关重要，而且对全球医学界也至关重要。一个合作的，以病人为导向的，具有成本效益的，文化敏感的方法必须在这一奋进的最前沿。虽然子宫肌瘤发展的确切发病机制仍然难以捉摸，种族差异是有据可查的。此外，在发达世界，妇女能够通过手术和非手术手段寻求治疗;然而，撒哈拉以南地区面临着自己的挑战，如果不加以解决，最终可能使许多遭受痛苦的妇女失去生命。不幸的是，关于如何预防纤维瘤发展的文献很少，这对于无法获得有效干预措施的妇女来说可能至关重要。我们小组和其他人最近的研究表明，维生素D缺乏在纤维瘤的发展中起着重要作用，可能是一个可预防的风险因素。每日补充维生素D是一种低成本、有效的干预措施，可以在整个撒哈拉以南地区实施。同样，对子宫肌瘤的性质和症状进行教育和提高认识，可以提高晚期子宫肌瘤患者的生活质量，消除负面的社会耻辱感，降低患病率和死亡率。
Black women carry the burden of uterine fibroids, (AKA uterine leiomyomas), at a much higher rate than their racial counterparts. Thus, increasing awareness and discovering a solution to an endemic problem that plagues Sub-Saharan Africa is of critical importance, not only for the region itself, but also for the medical community globally. A collaborative, patient oriented, cost effective, and culturally sensitive approach must be at the forefront of this endeavor. While the exact pathogenesis of uterine fibroid development remains elusive, the racial disparity is well documented. Moreover, in the developed world, women are able to seek treatment through surgical and non-surgical means; however, sub-Saharan regions face their own challenges that, if not addressed, can ultimately extinguish the lives of many suffering women. Unfortunately, the literature is scarce on how to prevent fibroid development, which may be critical for women who do not have access to effective interventions. Recent research from our group and others has shown that vitamin D deficiency plays an important role in fibroid development and may be a preventable risk factor. Daily vitamin D supplementation is a low cost, effective intervention that could be implemented throughout the Sub-Saharan region. Similarly, education and increased awareness as to the nature and symptoms of uterine fibroids could improve the quality of life, remove negative social stigma, and reduce morbidity and mortality rates in women who seek medical care with advanced uterine fibroids.