DATA: Diafiltration Apparatus for high-Throughput Analysis
DATA: Diafiltration Apparatus for high-Throughput Analysis
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DOI：
10.1016/j.memsci.2021.119743
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发表时间：
2022-01
影响因子：
9.5
通讯作者：
J. A. Ouimet;Xinhong Liu;David J. Brown;Elvis A. Eugene;Tylar Popps;Zachary W. Muetzel;A. Dowling;W. Phillip
中科院分区：
文献类型：
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作者：
J. A. Ouimet;Xinhong Liu;David J. Brown;Elvis A. Eugene;Tylar Popps;Zachary W. Muetzel;A. Dowling;W. Phillip
改进的表征技术，解决知识差距有关的界面过程，管理溶质-溶质的选择性和复杂的多组分进料流中的膜的性能，是必要的，以推进膜过程。在这项研究中，在数据科学工具的指导下，开发了一种渗滤装置，通过在广泛的进料溶液组成范围内快速表征膜性能，为材料和工艺设计提供信息。该装置将固定浓度的渗滤液溶液定量加入搅拌池中，以实现渗余物浓度的预定变化。在此，使用80 mM氯化钾（KCl）渗滤液溶液，结果表明，在5 mM至80 mM KCl相空间内，一次渗滤实验（8 h）可以比使用传统过滤工艺（47 h）的实验活动快五倍地探测膜性能。此外，数据分析和仪器之间的协同作用导致了在线电导率探针的引入，该探针监测实时渗余物浓度。这些额外的信息提供了关键的见解，以区分控制膜分离的机制（例如，区分基于吸附或排斥的分离），并允许精确测定膜传输系数。最后，结合适当的管理现象确定了一套自洽的商业NF 90膜的传输参数。
Improved characterization techniques, which address knowledge gaps related to the interfacial processes that govern solute–solute selectivity and the performance of membranes in complex multi-component feed streams, are necessary to advance membrane processes. In this study, guided by the tools of data science, a diafiltration apparatus is developed to inform material and process design by rapidly characterizing membrane performance over a broad range of feed solution compositions. The apparatus doses a fixed-concentration diafiltrate solution into a stirred cell to achieve a predetermined change in the retentate concentration. Here, using an 80 mM potassium chloride (KCl) diafiltrate solution, it was shown that membrane performance, within a 5 mM to 80 mM KCl phase space, could be probed five times more quickly with one diafiltration experiment (8 h) than with an experimental campaign using traditional filtration processes (47 h). Additionally, the synergy between data analytics and instrumentation led to the incorporation of an inline conductivity probe that monitored the real-time retentate concentration. This additional information provided key insights to distinguish between the mechanisms that govern membrane separations (e.g., discriminating between adsorption or rejection based separations) and allowed for the membrane transport coefficients to be determined accurately. Ultimately, incorporating the appropriate governing phenomena identified a single set of self consistent transport parameters for commercial NF90 membranes.