The Evidence for Present-Centered Therapy as a Treatment for Posttraumatic Stress Disorder

The Evidence for Present-Centered Therapy as a Treatment for Posttraumatic Stress Disorder
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DOI:
10.1002/jts.21881
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发表时间:
2014-02-01
影响因子:
3.3
通讯作者:
Wampold, Bruce E.
Wampold, Bruce E.
中科院分区:
医学3区
文献类型:
--
作者:
Frost, Nickolas D.;Laska, Kevin M.;Wampold, Bruce E.

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为了检查以现在为中心的治疗(PCT)作为创伤后应激障碍(PTSD)治疗的证据,对5项比较PCT与现有循证治疗PTSD的随机临床试验进行了综述。使用荟萃分析估计目标指标、次要指标和脱落的治疗间差异。在5项试验中的3项中,发现PCT与循证对照治疗一样有效,在纳入无治疗条件的2例病例中,PCT上级,目标变量的效应量较大(d = 0.88、0.74和1.27)。当使用荟萃分析汇总结果时,PCT与循证治疗对靶向和次要指标的影响较小且不显著(分别为d = 0.13和d = 0.09)。同样,PCT的脱落率显著低于对照循证治疗(分别为14.3%和31.3%)。PCT似乎是一种有效且可接受的PTSD治疗方法。
To examine the evidence for present-centered therapy (PCT) as a treatment for posttraumatic stress disorder (PTSD), 5 randomized clinical trials that compared PCT to an existing evidence-based treatment for PTSD were reviewed. A meta-analysis was used to estimate between-treatment differences on targeted measures, secondary measures, and dropout. PCT was found to be as efficacious as the comparison evidence-based treatment in 3 of the 5 trials, and in the 2 cases where a no-treatment condition was included, PCT was superior, with large effect sizes for targeted variables (d = 0.88, 0.74, and 1.27). When results were aggregated using meta-analysis, effects for PCT versus an evidence-based treatment for both targeted and secondary measures were small and nonsignificant (d = 0.13 and d = 0.09, respectively). As well, the dropout rate for PCT was significantly less than for the comparison evidence-based treatments (14.3% and 31.3%, respectively). It appears that PCT is an efficacious and acceptable treatment for PTSD.