Sitting Time and Mortality from All Causes, Cardiovascular Disease, and Cancer
Sitting Time and Mortality from All Causes, Cardiovascular Disease, and Cancer
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DOI：
10.1249/mss.0b013e3181930355
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发表时间：
2009-05-01
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影响因子：
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通讯作者：
Bouchard, Claude
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文献类型：
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作者：
Katzmarzyk, Peter T.;Church, Timothy S.;Bouchard, Claude
题名/责任者：[by]C.静坐时间和各种原因的死亡率，心血管疾病，癌症，医学。SCI。《体育运动》，第41卷，第5期，第998-1005页，2009年。目的：尽管中等到剧烈的体力活动与过早死亡有关，但久坐行为与死亡率之间的关系尚未得到充分的研究，可能代表了与缺乏运动相关的不同范式。我们前瞻性地调查了17,013名18-90岁的加拿大人的坐着时间和死亡率。方法：在基线水平上评估每天坐着的时间(几乎不坐时间、四分之一时间、一半时间、四分之三时间、几乎所有时间)、闲暇时间、身体活动、吸烟状况和饮酒情况。为了确定死亡率状况，对参与者进行了平均12.0年的前瞻性跟踪。结果：在204,732人年的随访中，共有1832人死亡(759人死于心血管疾病，547人死于癌症)。在调整了潜在的混杂因素后，所有原因引起的坐着时间越长，死亡风险越高(风险比(H-R)：1.00 1.00，1.11，1.36，1.54；P代表趋势
KATZMARZYK, P. T., T. S. CHURCH, C. L. CRAIG, and C. BOUCHARD. Sitting Time and Mortality from All Causes, Cardiovascular Disease, and Cancer, Med. Sci. Sports Exerc., Vol. 41, No. 5. pp. 998-1005, 2009. Purpose: Although moderate-to-vigorous physical activity is related to premature mortality, the relationship between sedentary behaviors and mortality has not been fully explored and may represent a different paradigm than that associated with lack of exercise. We prospectively examined sitting time and mortality in a representative sample of 17,013 Canadians 18-90 yr of age. Methods: Evaluation of daily sitting time (almost none of the time, one fourth of the time, half of the time, three fourths of the time, almost all of the time), leisure time physical activity, smoking status, and alcohol consumption was conducted at baseline. Participants were followed prospectively for an average of 12.0 yr for the ascertainment of mortality status. Results: There were 1832 deaths (759 of cardiovascular disease (CVD) and 547 of cancer) during 204,732 person-yr of follow-up. After adjustment for potential confounders, there was a progressively higher risk of mortality across higher levels of sitting time from all causes (hazard ratios (H R): 1.00 1.00, 1.11, 1.36, 1.54; P for trend