No association of depression and anxiety with the metabolic syndrome: the Norwegian HUNT study
No association of depression and anxiety with the metabolic syndrome: the Norwegian HUNT study
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DOI：
10.1111/j.1600-0447.2008.01315.x
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发表时间：
2009-07-01
影响因子：
6.7
通讯作者：
Dahl, A. A.
中科院分区：
文献类型：
--
作者：
Hildrum, B.;Mykletun, A.;Dahl, A. A.
目的：研究抑郁和焦虑与代谢综合征的关系。方法：对9571名年龄在20-89岁的Nord-Trondelag健康研究（HUNT 2）参与者进行横断面研究。我们评估了焦虑和抑郁与医院焦虑和抑郁量表和代谢综合征与国际糖尿病联盟criteria.Results：尽管慷慨的统计权力和使用连续和分类的方法，我们发现焦虑或抑郁和代谢综合征之间没有关联的模型调整年龄，性别，教育水平，吸烟，体力活动和脉搏率。当仅调整年龄和性别时，我们发现当使用连续测量时，抑郁症有弱的正相关，但不是在病例水平上。研究结果是相似的跨性别，和强大的排除心血管疾病和抗抑郁药。结论：在这个最大的研究，迄今为止，我们发现没有关联的焦虑和抑郁与代谢综合征。
Objective: To examine the associations of depression and anxiety with the metabolic syndrome.Method: Cross-sectional study of 9571 participants aged 20-89 years in the Nord-Trondelag Health Study (HUNT 2). We assessed anxiety and depression with the Hospital Anxiety and Depression Scale and the metabolic syndrome with the International Diabetes Federation criteria.Results: Despite generous statistical power and use of both continuous and categorical approaches, we found no association between anxiety or depression and the metabolic syndrome in models adjusted for age, gender, educational level, smoking, physical activity and pulse rate. When adjusted for age and gender only, we found a weak positive association for depression when a continuous measure was used, but not at the case level. The findings were similar across sexes, and robust for exclusion of cardiovascular disease and antidepressants.Conclusion: In this largest study to date we found no association of anxiety and depression with the metabolic syndrome.