SARCOID MACROPHAGE GIANT-CELLS - ULTRASTRUCTURE AND LYSOZYME CONTENT
SARCOID MACROPHAGE GIANT-CELLS - ULTRASTRUCTURE AND LYSOZYME CONTENT
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DOI：
10.1007/bf02889023
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发表时间：
1980-01-01
期刊：
影响因子：
--
通讯作者：
CARR, I
中科院分区：
文献类型：
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作者：
CARR, I
用电镜和电镜免疫细胞化学技术检查[人]肉样肉芽肿显示，肉样巨噬细胞巨细胞富含溶菌酶，呈致密颗粒状存在于合胞体中心。直径200纳米。合胞体的超微结构是一个活性分泌细胞的超微结构，表明肉瘤样巨噬细胞巨细胞是一个活性产生和储存溶菌酶的细胞，而不是产生溶菌酶的单核细胞的融合产物，也不是被摄取的溶菌酶的储存部位。
Examination of [human] sarcoid granuloma by EM and EM immunocytochemical techniques shows that the sarcoid macrophage giant cell is rich in lysozyme, present within the center of the syncytium in dense granules .apprx. 200 nm in diameter. The ultrastructure of the syncytium is that of an active secretory cell, suggesting that the sarcoid macrophage giant cell actively produces and stores lysozyme rather than being a fusion product of mononuclear cells which produce lysozyme or being a site of storage of ingested lysozyme.