Fertility and pregnancy outcomes in men and women with cystic fibrosis in the United Kingdom
Fertility and pregnancy outcomes in men and women with cystic fibrosis in the United Kingdom
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DOI：
10.1093/humrep/deh405
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发表时间：
2004-10-01
影响因子：
6.1
通讯作者：
Murphy, DJ
中科院分区：
文献类型：
--
作者：
Boyd, JM;Mehta, A;Murphy, DJ
背景：囊性纤维化 (CF) 患者的生存期现在已达四十岁。我们的目的是评估英国大型队列中患有囊性纤维化的男性和女性的生育能力和妊娠结局。方法：一项基于人群的队列研究，纳入 2001 年在英国囊性纤维化数据库注册的 4659 名男性和女性。结果：呼吸系统健康状况不佳（1 秒 FEV1 的用力呼气量）
BACKGROUND: The survival of patients with cystic fibrosis (CF) now occurs into the fourth decade of life. Our aim was to evaluate the fertility and pregnancy outcomes of men and women with cystic fibrosis within a large British cohort. METHODS: A population based cohort study of 4659 males and females registered with the UK Cystic Fibrosis Database in 2001. RESULTS: Poor respiratory health (forced expiratory volume in 1 s FEV1