Investigation of multifocal visual evoked potential in anisometropic and esotropic amblyopes.
Investigation of multifocal visual evoked potential in anisometropic and esotropic amblyopes.
复制标题
屈光参差性和内向性弱视的多焦视觉诱发电位的研究。
DOI：
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发表时间：
1998
影响因子：
4.4
通讯作者：
M. Edwards
中科院分区：
文献类型：
--
作者：
M. Yu;B. Brown;M. Edwards
目的
目的探讨内向性弱视和屈光参差性弱视在不同视野偏心率下视觉诱发电位（VEP）功能的变化。
方法
分析了 5 只内向性弱视眼、6 只屈光参差性弱视眼和 45 只对照眼的数据。 VERIS 系统用于在计算机显示器上生成包含 61 个六边形的刺激矩阵。显示器的每个六边形都包含许多黑色和白色的小六边形斑块，这些六边形斑块在刺激过程中根据伪随机二进制 m 序列反转极性。 VERIS 系统通过输入和输出信号的互相关来提取本地响应。分析了视野中央 8.6 度弧的反应潜伏期和幅度。
结果
在内斜性弱视中，多焦点 VEP 潜伏期延长，并且视野中央区域的幅度减小。颞侧视野中的平均振幅明显小于鼻侧视野中的平均振幅，并且平均潜伏期明显更长。在屈光参差性弱视中，潜伏期明显延长，并且多焦视觉诱发电位的振幅在视野的中心区域减弱，而这些影响在周边区域减弱。
结论
结果与心理物理学研究一致，报告显示弱视的中心凹缺陷更大，颞区的视力损失比内向性弱视的鼻区更大。
PURPOSE
To investigate the variation of visual evoked potential (VEP) function at different eccentricities of the visual field in esotropic amblyopes and anisometropic amblyopes.
METHODS
Data from 5 esotropic amblyopic eyes, 6 anisometropic amblyopic eyes, and 45 control eyes were analyzed. A VERIS system was used to generate a stimulus matrix containing 61 hexagons on a computer monitor. Each hexagon of the display contained a number of small black and white hexagonal patches that reversed in polarity during stimulation according to a pseudorandom binary m-sequence. The VERIS system extracted the local responses by cross-correlating the input and output signals. The latencies and amplitudes of the responses from the central 8.6 degrees of arc in the visual field were analyzed.
RESULTS
In esotropic amblyopia, the multifocal VEP latency is prolonged, and the amplitude is reduced in the central region of the visual field. The mean amplitude is significantly smaller, and the mean latency is significantly longer in the temporal visual field than in the nasal visual field. In anisometropic amblyopia, latencies are markedly prolonged, and the amplitudes of multifocal VEP are attenuated in the central region of the visual field, and these effects are lessened in the periphery.
CONCLUSIONS
The results are in agreement with psychophysical studies reporting a greater foveal deficit in amblyopia and a greater visual loss in the temporal field than in the nasal field in esotropic amblyopia.
影响因子：
4.4
作者：
C. Tyler;P. Apkarian;D. M. Levi;K. Nakayama
通讯作者：
C. Tyler;P. Apkarian;D. M. Levi;K. Nakayama