High dietary phosphate intake reduces bone strength in the growing rat skeleton

High dietary phosphate intake reduces bone strength in the growing rat skeleton
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DOI:
10.1359/jbmr.061009
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发表时间:
2007-01-01
影响因子:
6.2
通讯作者:
Lamberg-Allardt, Christel J. E.
Lamberg-Allardt, Christel J. E.
中科院分区:
医学1区
文献类型:
--
作者:
Huttunen, Minna M.;Tillman, Ilse;Lamberg-Allardt, Christel J. E.

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营养影响成年早期骨量发育的高峰。在为期8周的干预中评估高膳食磷酸盐摄入量对1月龄雄性大鼠(n = 30)骨骼生长的影响。高膳食磷酸盐摄入量增加骨重塑和损伤骨材料性能,降低骨的机械强度。
Nutrition influences peak bone mass development in early adulthood. The effect of high dietary phosphate intake on the growing skeleton of I-month-old male rats (n = 30) was assessed in an 8-week intervention. High dietary phosphate intake increased bone remodeling and impaired bone material properties, diminishing bone mechanical strength.