Anorexia Nervosa and Autism Spectrum Disorder: A Systematic Review
Anorexia Nervosa and Autism Spectrum Disorder: A Systematic Review
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DOI：
10.1016/j.psychres.2021.114271
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发表时间：
2021-11-17
影响因子：
11.3
通讯作者：
Sapuppo, Walter
中科院分区：
文献类型：
--
作者：
Boltri, Margherita;Sapuppo, Walter
背景：最近的研究表明，人们对探索神经性厌食症(AN)和自闭症谱系障碍(ASD)之间的关系越来越感兴趣。这两种情况似乎都有共同的认知、社会和行为损害领域，导致对治疗的相关影响，特别是在它们合并患病的情况下。这篇文献综述旨在综合这一主题的最新研究，以调查AN和ASD的并存情况，提出未来的研究方向，并考虑对治疗的影响。方法：采用Prisma指南，通过PubMed、EBSCOhost、Scope us和Web of Science进行系统检索。结果：13项研究符合资格标准，因此纳入审查。结果似乎证实了ASD症状在AN中的过度表现。只有几项研究调查了年轻人的AN-ASD共病，并且报告的发病率略低于成年人。结论：分析研究表明，虽然共病似乎加剧了病情的严重性，但自闭症的特征似乎随着时间的推移相当稳定，与体重无关。因此，未来的纵向研究和针对性别的评估工具可以帮助澄清这两种疾病之间的关系，检查ASD症状的开始，并制定结构化的治疗指南。
Background: Recent research has shown a growing interest in exploring the relationship between anorexia nervosa (AN) and autism spectrum disorder (ASD). Both conditions seem to share areas of cognitive, social and behavioural impairment, leading to relevant implications on treatment, especially when they are in comorbidity. This literature review aims to synthesise the latest studies on this topic to investigate the co-occurrence of AN and ASD, suggest future research directions and consider implications for treatment. Method: Records were systematically (PRISMA guidelines) identified through PubMed, EBSCOhost, Scopus and Web of Science searching. Results: Thirteen studies met the eligibility criteria and were therefore included in the review. Results seem to confirm an overrepresentation of ASD symptoms in AN. Only few studies investigated the AN-ASD comorbidity in young people and report slightly lower rates than those conducted with adults. Conclusions: Analysed studies suggest that while the comorbidity seems to exacerbate the severity of the condition, autistic traits appear to be rather stable over time and not related to body weight. Thus, future longitudinal studies and gender- specific assessment tools can help clarify the relationship between the two disorders, examine the onset of ASD symptoms and develop structured guidelines for treatment.