Involvement of the sympathetic nervous system in tetanus. Studies on 82 cases.
Involvement of the sympathetic nervous system in tetanus. Studies on 82 cases.
复制标题
破伤风涉及交感神经系统。
DOI：
10.1016/s0140-6736(68)92350-7
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发表时间：
1968
期刊：
影响因子：
168.9
通讯作者：
J. Spalding
中科院分区：
文献类型：
--
作者：
J. Kerr;J. L. Corbett;C. Prys‐roberts;A. Smith;J. Spalding
回顾性研究描述了一系列的82例破伤风患者，其中44人进行了气管切开术，curarisation，间歇性正压通气治疗。重度破伤风患者可能出现特征性综合征，其特征包括持续但不稳定的高血压和心动过速、心律不齐、外周血管收缩、多汗、发热、二氧化碳排出量增加、尿儿茶酚胺排泄增加，在某些情况下，晚期出现低血压。有人认为，这种综合征可能是由于持续但波动过度活跃的交感神经系统。
Retrospective studies are described on a series of 82 patients with tetanus, 44 of whom were treated by tracheostomy, curarisation, and intermittent positive-pressure ventilation. Patients with severe tetanus may develop a characteristic syndrome whose features include sustained but labile hypertension and tachycardia, irregularities of cardiac rhythm, peripheral vascular constriction, profuse sweating, pyrexia, increased carbon-dioxide output, increased urinary catecholamine excretion, and, in some cases, the late development of hypotension. It is argued that this syndrome may be due to continuous but fluctuating overactivity of the sympathetic nervous system.