A portable scanner for brain MRI
A portable scanner for brain MRI
复制标题
用于脑 MRI 的便携式扫描仪
DOI：
--
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发表时间：
2020
影响因子：
28.1
通讯作者：
L. Wald
中科院分区：
文献类型：
--
作者：
C. Cooley;Patrick C. McDaniel;J. Stockmann;S. Srinivas;S. Cauley;Monika Śliwiak;Charlotte R. Sappo;Christopher F. Vaughn;B. Guérin;M. Rosen;M. Lev;L. Wald
获得用于磁共振成像（MRI）的扫描仪通常受到成本和基础设施要求的限制。在这里，我们报告的设计和测试的便携式原型扫描仪的大脑MRI，使用一个紧凑，轻便的永磁稀土磁铁与内置的读出场梯度。122公斤的低场（80 mT）磁铁具有Halbach圆柱体设计，导致最小的杂散磁场，既不需要低温也不需要外部电源。内置的磁场梯度降低了对高功率梯度驱动器的依赖，降低了对电源和冷却的总体要求，并降低了噪声。在编码领域的不完善之处减轻了利用以前的表征的字段模式的广义迭代图像重建技术。在健康成年志愿者中，扫描仪可以生成T1加权、T2加权和质子密度加权脑图像，空间分辨率为2.2 × 1.3 × 6.8 mm3。未来版本的扫描仪可以提高在护理点进行脑部MRI的可及性，特别是对于重症患者。一种用于脑部MRI的便携式原型扫描仪，使用一种紧凑、轻便的永磁稀土磁体，内置读出场梯度，生成与临床相关的大脑图像，如成人志愿者所示。
Access to scanners for magnetic resonance imaging (MRI) is typically limited by cost and by infrastructure requirements. Here, we report the design and testing of a portable prototype scanner for brain MRI that uses a compact and lightweight permanent rare-earth magnet with a built-in readout field gradient. The 122-kg low-field (80 mT) magnet has a Halbach cylinder design that results in a minimal stray field and requires neither cryogenics nor external power. The built-in magnetic field gradient reduces the reliance on high-power gradient drivers, lowering the overall requirements for power and cooling, and reducing acoustic noise. Imperfections in the encoding fields are mitigated with a generalized iterative image reconstruction technique that leverages previous characterization of the field patterns. In healthy adult volunteers, the scanner can generate T1-weighted, T2-weighted and proton density-weighted brain images with a spatial resolution of 2.2 × 1.3 × 6.8 mm3. Future versions of the scanner could improve the accessibility of brain MRI at the point of care, particularly for critically ill patients. A portable prototype scanner for brain MRI that uses a compact and lightweight permanent rare-earth magnet with a built-in readout field gradient generates clinically relevant images of the brain, as shown in adult volunteers.
DOI：
10.1016/j.jmr.2016.04.005
发表时间：
2016-07
期刊：
Journal of magnetic resonance (San Diego, Calif. : 1997)
影响因子：
--
作者：
Stockmann JP;Cooley CZ;Guerin B;Rosen MS;Wald LL
通讯作者：
Wald LL