Kitchens as a source of Aspergillus niger infection
Kitchens as a source of Aspergillus niger infection
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DOI：
10.1016/s0195-6701(96)90145-0
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发表时间：
1996-03-01
影响因子：
6.9
通讯作者：
Morris, CQ
中科院分区：
文献类型：
--
作者：
Loudon, KW;Coke, AP;Morris, CQ
在这项研究中，我们调查了一组由黑曲霉引起的皮肤感染的流行病学，这种感染发生在骨髓移植单位的中性粒细胞减少的患者中。在该单位毗邻的病房厨房内，发现霉菌对环境造成严重污染。对临床分离株和环境分离株进行随机扩增多态性DNA(RAPD)分型，结果表明其中一例患者感染的菌株与从厨房地区反复分离的菌株相同。在另一起案件中，受污染的短袜材料被认为是感染源。对病房厨房的彻底清洁导致该单位没有进一步的案件发生。这突出了曲霉菌可能通过空气、食物或其他交通工具传播给患者的事实，并强调了寻找来源和确保保持高水平医院卫生的重要性。
In this study we investigated the epidemiology of a cluster of cutaneous infections owing to Aspergillus niger, which occurred in neutropenic patients in a bone marrow transplant unit. Heavy environmental contamination with the mould was found in the ward kitchen adjacent to the unit. The clinical and environmental isolates were typed by random amplification of polymorphic DNA (RAPD), which showed one of the patients was infected with the same strain as that isolated repeatedly from the kitchen area. In another case, contaminated stockinette material was implicated as the source of infection. Thorough cleaning of the ward kitchen resulted in no further cases on the unit. This highlights the fact that aspergilli may spread to patients by air, food or other vehicles, and underlines the importance of searching for a source and ensuring high levels of hospital hygiene are maintained.