Medial prefrontal cell activity signaling prediction errors of action values
Medial prefrontal cell activity signaling prediction errors of action values
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DOI：
10.1038/nn1890
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发表时间：
2007-05-01
影响因子：
25
通讯作者：
Tanaka, Keiji
中科院分区：
文献类型：
--
作者：
Matsumoto, Madoka;Matsumoto, Kenji;Tanaka, Keiji
为了使行为适应不断变化的环境，人们必须监控所执行行为的结果，并相应地调整后续行为。内侧额叶皮层参与性能监测已被提出，但很少有人知道的神经过程，性能监测性能调整。在这里，我们记录了猴子内侧前额叶皮层的神经元学习任意行动-结果偶然性。一些细胞优先对正视觉反馈刺激作出反应，而另一些细胞则对负反馈刺激作出反应。在行为适应过程中，对正反馈刺激的反应幅度下降，与动作值的预测误差量下降相关。因此，内侧前额叶细胞中的这些反应可能会发出信号，在执行的动作的值的预测中的错误的方向和量，以指定在随后的动作选择的调整。
To adapt behavior to a changing environment, one must monitor outcomes of executed actions and adjust subsequent actions accordingly. Involvement of the medial frontal cortex in performance monitoring has been suggested, but little is known about neural processes that link performance monitoring to performance adjustment. Here, we recorded from neurons in the medial prefrontal cortex of monkeys learning arbitrary action- outcome contingencies. Some cells preferentially responded to positive visual feedback stimuli and others to negative feedback stimuli. The magnitude of responses to positive feedback stimuli decreased over the course of behavioral adaptation, in correlation with decreases in the amount of prediction error of action values. Therefore, these responses in medial prefrontal cells may signal the direction and amount of error in prediction of values of executed actions to specify the adjustment in subsequent action selections.