INTERSTITIAL LASER PHOTOCOAGULATION AS A TREATMENT FOR BREAST-CANCER
INTERSTITIAL LASER PHOTOCOAGULATION AS A TREATMENT FOR BREAST-CANCER
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DOI：
10.1002/bjs.1800811118
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发表时间：
1994-11-01
影响因子：
9.6
通讯作者：
BOWN, SG
中科院分区：
文献类型：
--
作者：
HARRIES, SA;AMIN, Z;BOWN, SG
这份初步报告描述了使用间质激光光凝治疗小型乳腺癌。 44 名患者在诊断和手术之间的间隔时间内在局部麻醉下接受了 805 nm 的二极管激光治疗。 42 名患者使用了超声波检查，两名患者使用了计算机断层扫描 (CT)，将光纤放置在肿瘤中并监测激光效果。激光诱导的切除肿瘤内的坏死直径从 0 毫米到 25 毫米不等。治疗后纤维尖端周围肿瘤中存在炭化与未发生炭化时相比，坏死直径显着增大（中位数 13 毫米与 6 毫米，P = 0.002）。预炭化纤维导致更可预测的坏死直径（中位 14 毫米）。超声检查在评估激光损伤方面不准确；动态CT和磁共振成像可能更有用。间质激光光凝术简单且安全，并且可以产生合理可预测程度的坏死。
This preliminary report describes the use of interstitial laser photocoagulation to manage small breast cancers. Forty-four patients were treated with a diode laser of 805 nm under local anaesthesia in the interval between diagnosis and surgery. Ultrasonography was used in 42 patients and computed tomography (CT) in two to place the fibre in the tumour and monitor laser effects. Laser-induced necrosis within the resected tumour varied from 0 to 25 mm in diameter. The presence of charring in the tumour around the fibre tip after treatment was associated with significantly larger diameters of necrosis than when charring did not occur (median 13 versus 6 mm, P = 0.002). Precharring the fibre resulted in a more predictable diameter of necrosis (median 14mm). Ultrasonography was inaccurate in assessing laser damage; dynamic CT and magnetic resonance imaging may be of more use. Interstitial laser photocoagulation is simple and safe, and can produce necrosis of a reasonably predictable extent.