A core outcome set for research on the management of otitis media with effusion in otherwise-healthy children
A core outcome set for research on the management of otitis media with effusion in otherwise-healthy children
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DOI：
10.1016/j.ijporl.2020.110029
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发表时间：
2020-07-01
影响因子：
1.5
通讯作者：
Daniel, Mat
中科院分区：
文献类型：
--
作者：
Liu, Paul Zhaobo;Ismail-Koch, Hasnaa;Daniel, Mat
核心结果集（COS）是所有研究报告的一个商定的结果域列表。有一种针对腭裂儿童中耳炎伴渗出性中耳炎（OME）的COS（称为MOMENT），但没有针对其他健康儿童的COS。本研究探讨MOMENT COS是否也适用于其他健康儿童。方法：通过三种方法生成一长串潜在结果（独立于MOMENT）：文献综述以确定OME研究报告了哪些结果，综述OME问卷中包含的结果，以及焦点小组询问OME患儿的父母对他们重要的事情。使用这些来源制定的长列表没有确定除了MOMENT长列表中的结果之外的结果。随后进行了一项在线问卷调查，询问父母/监护人和专业人员/研究人员是否认为MOMENT的最终结果也适用于其他方面健康的儿童。结果：共有134人参与：53名家长/监护人（通过英国NHS医院招募）和81名专业人员/研究人员（国际招募）。总体而言，128人（95.5%）同意MOMENT的结果也适用于其他方面健康的儿童（100%为父母/监护人，92.6%为专业人员/研究人员）。结论：在腭裂儿童OME治疗的COS中确定的结果域也可用于其他健康儿童。
Introduction: A Core Outcome Set (COS) is an agreed list of outcome domains to be reported by all studies investigating a condition. A COS for Otitis Media with Effusion (OME) in children with cleft palate exists (called MOMENT), but there isn't one for otherwise-healthy children. This study investigates whether the MOMENT COS could also be applicable to otherwise-healthy children.Methods: A long list of potential outcomes was generated (independently of MOMENT) via three methods: literature review to establish which outcomes are reported by OME studies, a review of outcomes contained in OME questionnaires, and a focus group asking parents of children with OME what matters to them. The long list drawn up using these sources identified no outcomes additional to ones in the MOMENT long list. An online questionnaire was subsequently undertaken, asking parents/guardians and professionals/researchers whether they think that the MOMENT final list outcomes would also be applicable to otherwise healthy children.Results: A total of 134 people took part: 53 parents/guardians (recruited through UK NHS hospitals) and 81 professionals/researchers (recruited internationally). Overall, 128 (95.5%) agreed that the MOMENT outcomes can also apply to otherwise healthy children (100% parents/guardians, 92.6% professionals/researchers).Conclusions: The outcome domains identified in the COS for OME management in children with cleft palate can also be used in otherwise-healthy children.