Recurrent Colorectal Cancer
Recurrent Colorectal Cancer
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复发性结直肠癌
DOI：
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发表时间：
2011
期刊：
影响因子：
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通讯作者：
J. García
中科院分区：
文献类型：
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作者：
M. Haddock;H. Nelson;V. Valentini;L. Gunderson;C. Willett;H. Rutten;F. Calvo;L. Harrison;W. Enker;J. García
对于原发性直肠癌或结肠癌切除术后局部或区域复发的患者，通常不考虑采用积极的、治愈性的治疗方法。越来越多的证据支持一种积极的方法，将体外照射（EBRT）±化疗、切除和术中照射（IORT）与全身化疗结合起来。本章将提供数据，总结来自美国和欧洲机构的含IORT方案的疾病控制和生存结果，包括预后因素对结果的影响以及既往接受过放射治疗的患者的结果。IORT耐受性和未来的潜力作为治疗的一个组成部分将进行讨论。
Aggressive, curative intent treatment approaches in patients with local or regional relapse after resection of primary rectal or colon cancers are often not considered. A growing body of evidence supports an aggressive approach combining external beam irradiation (EBRT) ± chemotherapy, resection, and intraoperative irradiation (IORT) in conjunction with systemic chemotherapy. Data will be presented in this chapter summarizing disease control and survival results with IORT-containing regimens from US and European institutions including the impact of prognostic factors on results and the results in previously irradiated patients. IORT tolerance and future potential as a component of treatment will be discussed.
影响因子：
158.5
作者：
OCONNELL, M;MARTENSON, JA;RICH, TA
通讯作者：
RICH, TA