Highly selective, sensitive and fluorescent sensing of dimeric G-quadruplexes by a dimeric berberine
Highly selective, sensitive and fluorescent sensing of dimeric G-quadruplexes by a dimeric berberine
复制标题
二聚小檗碱对二聚 G-四链体的高选择性、灵敏和荧光传感
DOI：
10.1039/c5ob01723h
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发表时间：
2016-01-01
影响因子：
3.2
通讯作者：
Chen, Wen-Hua
中科院分区：
文献类型：
--
作者：
Zhou, Chun-Qiong;Yang, Jian-Wei;Chen, Wen-Hua
本文描述了聚醚系二聚体小檗碱1对二聚体g -四聚物的高选择性、灵敏度和拓扑特异性荧光传感。化合物1对二聚体g -四聚体的选择性高于单体g -四聚体，并且可以被二聚体g -四聚体，特别是与一个TTA亚基连接的g -四聚体点燃。此外，它对g -四络合物的拓扑结构和热稳定性没有影响。
This paper describes the highly selective, sensitive and topology-specific fluorescent sensing of dimeric G-quadruplexes by a polyether-tethered dimeric berberine 1. Compound 1 displays high selectivity for dimeric G-quadruplexes over monomeric ones, and can be lit up by dimeric G-quadruplexes, in particular by the one linked with one TTA subunit. In addition, it shows no effect on the topology or thermal stability of the G-quadruplexes.