Long-term dietary and weight changes following a short-term dietary intervention study: EVADE-CAD trial follow-up.
Long-term dietary and weight changes following a short-term dietary intervention study: EVADE-CAD trial follow-up.
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DOI：
10.1097/mca.0000000000001072
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发表时间：
2022-03-01
影响因子：
1.8
通讯作者：
Shah B
中科院分区：
文献类型：
--
作者：
Dogra S;Woolf K;Xia Y;Getz A;Newman JD;Slater J;Shah B
Diet-centered therapies improve inflammatory, lipid and glycemic profiles [1]. The randomized Effects of a Vegan diet versus American Heart Association (AHA)–Recommended DiEt in Coronary Artery Disease (EVADE-CAD) trial demonstrated a greater reduction in C-reactive protein and low-density lipoprotein cholesterol with a vegan versus AHA-recommended diet in patients with coronary artery disease [2, 3]. The 8-week intervention included provision of weekly groceries, a 2-week sample menu, vegan/AHA cookbook, measuring tools and at least twice weekly contact with a registered dietitian [2]. The hypothesis of this follow-up study was that the EVADE-CAD trial design, which provided tools to assist participants in adhering to their assigned diet rather than the provision of prepared meals, would provide skills that participants could implement beyond the end of the study and confer sustained dietary adherence and weight loss on follow-up. A secondary hypothesis was that this long-term adherence would not vary between participants initially assigned to the vegan versus AHA diet.Participants underwent telephone follow-up at 3 months, 6 months and yearly up to 4 years for data on dietary adherence, self-reported healthiness of current diet on a 5-point scale, self-reported weight and major adverse cardiovascular events (MACE; composite of death, cardiac arrest, myocardial infarction, revascularization, heart failure and stroke). Adherence was determined (1) from a random 24-h dietary recall as previously described and (2) per patient’s self-report of whether or not they were adherent to their initially assigned diet [2, 3]. Data were compared using Mann–Whitney tests for continuous variables and the chisquare tests for categorical variables. Within group changes from baseline assessment were assessed using Wilcoxon signed-rank tests and the Kaplan–Meier method was used for MACE events. Statistical analyses were performed using SPSS Statistics Version 25 (IBM, New York, USA).
