HBV transmission from an occult carrier with five mutations in the major hydrophilic region of HBsAg to an immunosuppressed plasma recipient

HBV transmission from an occult carrier with five mutations in the major hydrophilic region of HBsAg to an immunosuppressed plasma recipient
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DOI:
10.1016/j.jcv.2013.06.020
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发表时间:
2013-09-01
影响因子:
8.8
通讯作者:
Petruzziello, Arnolfo
Petruzziello, Arnolfo
中科院分区:
医学3区
文献类型:
--
作者:
Coppola, Nicola;Loquercio, Giovanna;Petruzziello, Arnolfo

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我们描述了一个病例,通过HBsAg阴性受试者的血浆捐赠,将HBsAg阴性的乙型肝炎感染传播给免疫抑制的患者,但血清HBV DNA非常低(约50 IU/ml),并且在HBsAg的主要亲水区域发生了5个突变。(C) 2013, Elsevier b.v.出版。
We describe the case of transmission of an HBsAg-negative hepatitis B infection to an immunosuppressed patient by plasma donation from an HBsAg-negative subject, but with very low serum HBV DNA (about 50 IU/ml) and five mutations in the major hydrophilic region of HBsAg. (C) 2013 Published by Elsevier B. V.