Newborn infection with Herpesvirus hominis types 1 and 2.
Newborn infection with Herpesvirus hominis types 1 and 2.
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新生儿感染人型疱疹病毒 1 型和 2 型。
DOI：
10.1016/s0022-3476(69)80375-6
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发表时间：
1969
期刊：
影响因子：
--
通讯作者：
C. Luce
中科院分区：
文献类型：
--
作者：
A. Nahmias;W. Dowdle;W. E. Josey;Z. Naib;L. M. Painter;C. Luce
对28例人疱疹病毒（HVH）感染的新生儿和（或）母亲的病毒和（或）血清进行了分型，其中25例为2型，3例为1型。这些实验室检查结果，加上一些母亲的临床资料，有力地表明母亲受感染的生殖道（95%以上是2型HVH）是新生儿疱疹感染的主要来源，从而为预防这种通常严重的新生儿感染提供了可能的方法。几个感染的婴儿表现出IgM血清水平的升高，这似乎更好地与HVH抗体检测的间接免疫荧光技术比中和试验。
Typing of viruses and/or sera obtained from infants and/or mothers in 28 cases of neonatal infection withHerpesvirus hominis(HVH) provided evidence of type 2 HVH infection in 25 and type 1 HVH infection in 3 of the newborn infants. These laboratory findings, coupled with clinical information on some of the mothers, point strongly to the mother's infected genital tract (over 95 per cent are type 2 HVH) as the major source of herpetic infection in the newborn, thus providing possible approaches to prevention of this usually severe newborn infection. Several of the infected infants demonstrated elevations of IgM serum levels which appeared to correlate better with HVH antibodies detected by an indirect immunofluorescent technique than by neutralization tests.