Intravascular Lithotripsy in Calcified Coronary Lesions A Prospective, Observational, Multicenter Registry
Intravascular Lithotripsy in Calcified Coronary Lesions A Prospective, Observational, Multicenter Registry
复制标题
DOI：
10.1161/circinterventions.119.008154
复制
发表时间：
2019-11-01
影响因子：
5.6
通讯作者：
Werner, Nikos
中科院分区：
文献类型：
--
作者：
Aksoy, Adem;Salazar, Carlos;Werner, Nikos
背景：钙化冠状动脉病变的最佳斑块准备是预防支架失效的关键。本研究的目的是确定血管内碎石术（IVL）在所有患者队列钙化病变中的策略成功率和安全性。方法：在3个中心筛选钙化冠状动脉病变患者。71例患者有资格接受IVL。患者被分配接受（A组）初次IVL治疗钙化新发病变患者（n=39处病变），（B组）二次IVL治疗钙化病变患者，其中非顺应性球囊扩张失败（n=22处病变），和（C组）三次IVL治疗既往支架植入术后支架膨胀不足的患者（n=17处病变）。主要终点是策略成功（支架扩张，
Background: Optimal plaque preparation of calcified coronary lesions is key to prevent stent failure. The purpose of this study was to determine the strategy success and safety of intravascular lithotripsy (IVL) in calcified lesions of an all-comers cohort. Methods: Patients with calcified coronary lesions were screened in 3 centers. Seventy-one patients were eligible for IVL. Patients were assigned to (group A) primary IVL therapy for patients with calcified de-novo lesions (n=39 lesions), (group B) secondary IVL therapy for patients with calcified lesions in which noncompliant balloon dilatation failed (n=22 lesions), and (group C) tertiary IVL therapy in patients with stent underexpansion after previous stenting (n=17 lesions). Primary end point was strategy success (stent expansion with