EFFECTS OF 2,3,7,8-TETRACHLORODIBENZO-PARA-DIOXIN (TCDD) ON EARLY LIFE STAGES OF RAINBOW-TROUT (SALMO-GAIRDNERI, RICHARDSON)
EFFECTS OF 2,3,7,8-TETRACHLORODIBENZO-PARA-DIOXIN (TCDD) ON EARLY LIFE STAGES OF RAINBOW-TROUT (SALMO-GAIRDNERI, RICHARDSON)
复制标题
DOI：
10.1016/0300-483x(81)90092-5
复制
发表时间：
1981-01-01
期刊：
影响因子：
4.5
通讯作者：
HELDER, T
中科院分区：
文献类型：
--
作者：
HELDER, T
将虹鳟鱼卵、卵黄囊苗和幼鱼分别暴露于不同浓度的2,3,7,8-四氯二苯并-对二恶英（某些除草剂的污染物，TCDD）中96 h。本研究中使用的最低浓度为0.1万亿分之一[ppt] (10-13 g/g)，对虹鳟鱼卵的生长造成了72天的显著迟缓。在较高的浓度下，大量即将到来的鱼苗出现全身性水肿并死亡。组织学上可见肝实质细胞变性、坏死。其余幼鱼表现为上颌骨缩短和眼部缺损等畸形改变。在卵黄囊苗中施用TCDD也有类似的效果。10和100 ppt TCCD处理96 h后，虹鳟鱼幼鱼生长迟缓，出现轻微的水肿变化。在100 ppt的实验中，所有的鱼苗都在27天内死亡。组织学上可见肝实质细胞空泡化，肝、胰、胃细胞内包涵体空泡化。
Rainbow trout eggs, yolk sac fry and juveniles were exposed to 2,3,7,8-tetrachlorodibenzo-p-dioxin [a contaminant of certain herbicides, TCDD] in different concentrations for 96 h. Exposure of eggs to the lowest concentration used in this study, 0.1 parts per trillion [ppt] (10-13 g/g), resulted in a significant growth retardation for 72 days. At higher concentrations significant numbers of the forthcoming fry developed generalized edemas and died. Histologically, degeneration and necrosis of liver parenchymal cells were observed. Remaining fry showed teratologic changes as foreshortened maxillas and opercular defects. Administration of TCDD to yolk sac fry has similar effects. Juvenile rainbow trout, exposed to 10 and 100 ppt TCCD for 96 h, showed growth retardation and developed slight edematous changes. At 100 ppt all fry had died within 27 days. Histologically, vacuolization of the liver parenchymal cells and intracellular inclusion bodies in liver, pancreas and stomach were observed.