Acute myocardial infarction with normal coronary artery: A case report and review of literature
Acute myocardial infarction with normal coronary artery: A case report and review of literature
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DOI：
10.1097/00000441-199711000-00013
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发表时间：
1997-11-01
影响因子：
3.1
通讯作者：
Jonas, EA
中科院分区：
文献类型：
--
作者：
Manzar, KJ;Padder, FA;Jonas, EA
一名没有冠状动脉疾病危险因素的 17 岁女孩患了急性心肌梗塞。她接受了组织型纤溶酶原激活剂的溶栓治疗。对心肌梗塞病因的广泛检查显示蛋白质 S 缺乏。血管造影显示冠状动脉正常。我们推测心肌梗塞的原因是冠状动脉痉挛或血栓形成，经溶栓治疗成功溶解。这是第八例冠状动脉正常但蛋白 S 缺乏的患者发生急性心肌梗塞的病例报告。我们回顾了有关心肌梗死和正常冠状动脉以及蛋白质 S 缺乏的文献。本病例报告和文献综述表明，有必要将冠状动脉疾病的经典危险因素的概念扩展到患有心肌梗塞和冠状动脉正常的年轻患者中。
A 17-year-old girl with no risk factors for coronary artery disease had acute myocardial infarction. She received thrombolytic therapy with tissue-type plasminogen activator. An extensive workup for the cause of myocardial infarction revealed protein S deficiency. Angiography showed normal coronary arteries. We speculate that the cause of myocardial infarction was coronary spasm or thrombus formation, which was successfully dissolved by thrombolytic therapy. This is the eighth case report of acute myocardial infarction in a patient with normal coronaries and protein S deficiency. We reviewed the literature concerning myocardial infarction and normal coronaries and protein S deficiency. This case report and review of the literature suggest the need to extend the concept of classic risk factors for coronary artery disease in young patients with myocardial infarction and normal coronary arteries.