Expanding Clinical Trials Designs to Extend Equitable Hearing Care.
Expanding Clinical Trials Designs to Extend Equitable Hearing Care.
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DOI：
10.1097/aud.0000000000001165
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发表时间：
2022-07-01
期刊：
影响因子：
3.7
通讯作者：
中科院分区：
文献类型：
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临床试验对于将科学创新转化为临床实践至关重要。听力保健依赖于这种转化方法来改善结果和生活质量。在整个医疗保健领域，临床试验缺乏多元化参与，未能招募和留住代表性不足和服务不足的人群，也没有向更广泛的人群严格传播和实施新研究。听力保健研究领域将受益于扩大临床试验的类型和设计，将听力保健和新的干预措施扩展到不同的人群，以及强调评估影响如何有效提供护理的因素的试验。本文探讨了以下问题：（1）临床试验的作用、价值和设计类型（随机对照、整群随机、阶梯楔形和混合方法），以解决健康公平问题;（2）整合社区和利益相关者参与的重要性;（3）临床试验的传播和实施框架和设计（混合试验设计）。通过采用更广泛的临床试验设计，听力保健研究人员或许能够将科学发现扩展到更多样化的人群。
Clinical trials are critically important to translate scientific innovations into clinical practice. Hearing healthcare depends on this translational approach to improve outcomes and quality of life. Across the spectrum of healthcare, there is a lack of diverse participation in clinical trials, a failure to recruit and retain underrepresented and underserved populations, and an absence of rigorous dissemination and implementation of novel research to broader populations. The field of hearing healthcare research would benefit from expanding the types and designs of clinical trials that extend hearing healthcare and novel interventions to diverse populations, as well as emphasizing trials that evaluate factors influencing how that care can be delivered effectively. This article explores the following: (1) the role, value, and design types of clinical trials (randomized controlled, cluster randomized, stepped wedge, and mixed methods) to address health equity; (2) the importance of integrating community and stakeholder involvement; and (3) dissemination and implementation frameworks and designs for clinical trials (hybrid trial designs). By adopting a broader range of clinical trial designs, hearing healthcare researchers may be able to extend scientific discoveries to a more diverse population.