EVIDENCE OF HETEROSIS IN MAN
EVIDENCE OF HETEROSIS IN MAN
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DOI：
10.1098/rspb.1955.0047
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发表时间：
1955-01-01
期刊：
影响因子：
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通讯作者：
PENROSE, LS
中科院分区：
文献类型：
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作者：
PENROSE, LS
在动物物种中，由于杂种优势而产生的平衡多态性原理已被接受多年，但将同一思想认真应用于人类却进展缓慢。人类实验育种是不可能的，并且在实验动物中可以证明的效果可能隐藏在随机育种群体中。另一方面，自然选择下的种群可能适合某些在实验工作中不可能进行的研究。人类存在某种混合活力的证据来自直接和间接测量。大多数证据都是间接的，但最初可以考虑对已知或假设的杂合子进行直接测量的少数例子。
In animal species the principle of balanced polymorphism due to heterosis has been accepted for many years, but the serious application of the same idea to man has been slow. Human experimental breeding is not possible, and effects, demonstrable in laboratory animals, may be concealed in a randomly breeding population. On the other hand, populations under natural selection may be suitable for certain kinds of studies not possible in experimental work. Evidence for the existence of some kind of hybrid vigour in man comes from both direct and indirect measurement. Most of the evidence is indirect, but the few examples of direct measurements on known or supposed heterozygotes may be considered initially.