Influence of nebulizer design and aerosol impact bead on analytical sensitivities of inductively coupled plasma mass spectrometry
Influence of nebulizer design and aerosol impact bead on analytical sensitivities of inductively coupled plasma mass spectrometry
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雾化器设计和气溶胶撞击珠对电感耦合等离子体质谱分析灵敏度的影响
DOI：
10.1016/j.sab.2010.08.006
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发表时间：
2010
期刊：
影响因子：
--
通讯作者：
J. Todolí
中科院分区：
文献类型：
--
作者：
E. Paredes;Jesús Bosque;J. Mermet;J. Todolí
在ICP-MS中研究了气动同心雾化器产生的气溶胶的特性以及灵敏度，共26个雾化器：17个A型，6个C型和3个K型。尽管设计相同，但在A1-30型雾化器中观察到灵敏度差异。自由输送速率，体积液滴尺寸分布中值D50与毛细管内径之间的关系，研究了雾化器气体出口横截面积对D50、从气体到液体流的能量传递效率和气雾剂锥体内的空间均匀性的影响。对于给定的雾化器设计，气体出口横截面积已显示出对气雾剂特性的关键影响。探讨了气溶胶的产生机理，并得出结论：A型雾化器的雾化效果优于C型和K型雾化器。根据所使用的特定喷雾器，喷雾室设计也对结果有显著影响。已经观察到，对于几个雾化器，样品毛细管相对于气体出口孔没有完全居中。为了最小化与这种不良对准相关联的问题（即，不同的灵敏度取决于喷雾器），可以使用配备有冲击珠的喷雾室，但这会损害灵敏度。
The characteristics of the aerosols generated by pneumatic concentric nebulizers as well as sensitivities were studied in ICP-MS with a total of 26 nebulizers: 17 of the A-type, 6 of the C-type, and 3 of the K-type. Although of the same design, discrepancies in sensitivity were observed among the A1-30 type nebulizers. Free delivery rate, relation between the median of the volume drop size distribution, D50, and the capillary i.d., effect of the nebulizer gas exit cross sectional area on D50, energy transfer efficiency from the gas to the liquid stream and spatial homogeneity within the aerosol cones were studied. For a given nebulizer design, the gas exit cross-sectional area has shown to critically influence the aerosol characteristics. The aerosol generation mechanism has been explored and it has been concluded that, for A-type nebulizers the nebulization is more efficient than for C and K-type ones. The spray chamber design has also a marked effect on the results according to the particular nebulizer used. It has been observed that sample capillary was not perfectly centered with regard to the gas exit bore for several nebulizers. In order to minimize the problems associated with this bad alignment (i.e., different sensitivity depending on the nebulizer), spray chambers equipped with impact beads may be used, but to the detriment of the sensitivity.