THE NUCLEOTIDE-SEQUENCE OF HUMAN RHINOVIRUS-1B - MOLECULAR RELATIONSHIPS WITHIN THE RHINOVIRUS GENUS
THE NUCLEOTIDE-SEQUENCE OF HUMAN RHINOVIRUS-1B - MOLECULAR RELATIONSHIPS WITHIN THE RHINOVIRUS GENUS
复制标题
DOI：
10.1099/0022-1317-69-1-49
复制
发表时间：
1988-01-01
影响因子：
3.8
通讯作者：
STANWAY, G
中科院分区：
文献类型：
--
作者：
HUGHES, PJ;NORTH, C;STANWAY, G
我们测定了人鼻病毒1B的核苷酸全序列，并与其它鼻病毒作了比较。与血清型2和89有广泛的同源性，但与血清型14的相似性要小得多。鼻病毒的特异性特征，特别是5“非编码区的长度和密码子使用的模式，已经被注意到，这些可能足以将鼻病毒定义为一个独特的属，而不是像以前建议的那样被认为是肠道病毒的成员。
We have determined the complete nucleotide sequence of human rhinovirus 1B and made comparisons with other rhinoviruses. Extensive homology was found with serotypes 2 and 89 but the similarity to serotype 14 was considerably less. Rhinovirus-specific characteristics have been noted, in particular the length of the 5'' non-coding region and the pattern of codon usage, and these may be sufficient to define the rhinoviruses as a distinct genus rather than being considered as members of the enteroviruses as has been suggested previously.