New method for comprehensive detection of chemical warfare agents using an electron-cyclotron-resonance ion-source mass spectrometer.
New method for comprehensive detection of chemical warfare agents using an electron-cyclotron-resonance ion-source mass spectrometer.
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使用电子回旋共振离子源质谱仪综合检测化学战剂的新方法。
DOI：
10.1016/j.saa.2010.12.052
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发表时间：
2011
期刊：
影响因子：
--
通讯作者：
M. Toda
中科院分区：
文献类型：
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作者：
M. Kidera;Y. Seto;Kazuya Takahashi;S. Enomoto;Shintaro Kishi;Mika Makita;T. Nagamatsu;Tatsuhiko Tanaka;M. Toda
我们开发了一种基于电子回旋共振离子源的元素分析系统的气相化学战剂检测技术。在将蒸气样品直接引入离子源之后，使用电子回旋共振等离子体将分子材料分解成元素并电离。检查了以下化学武器和兴奋剂：氟膦酸二异丙酯（DFP）、2-氯乙基乙基硫醚（2CEES）、氯化氰（CNCl）和氰化氢（HCN）。化学战剂的类型，具体来说，是神经毒剂、起泡剂、血液毒剂还是窒息剂，可以通过使用质谱法测量单原子离子或CN+的数量来确定。这是可能的，以检测气体化学武器，不能检测到的常规质谱仪。通过调节用于产生电子回旋共振等离子体的微波的输入功率，可以精确地控制等离子体中的电子温度分布，并且目标化合物可以被检测为分子离子或碎片离子，从而能够识别目标试剂。
We developed a detection technology for vapor forms of chemical warfare agents (CWAs) with an element analysis system using an electron cyclotron resonance ion source. After the vapor sample was introduced directly into the ion source, the molecular material was decomposed into elements using electron cyclotron resonance plasma and ionized. The following CWAs and stimulants were examined: diisopropyl fluorophosphonate (DFP), 2-chloroethylethylsulfide (2CEES), cyanogen chloride (CNCl), and hydrogen cyanide (HCN). The type of chemical warfare agents, specifically, whether it was a nerve agent, blister agent, blood agent, or choking agent, could be determined by measuring the quantities of the monatomic ions or CN+using mass spectrometry. It was possible to detect gaseous CWAs that could not be detected by a conventional mass spectrometer. The distribution of electron temperature in the plasma could be closely controlled by adjusting the input power of the microwaves used to generate the electron cyclotron resonance plasma, and the target compounds could be detected as molecular ions or fragment ions, enabling identification of the target agents.