RADIOIMMUNOASSAY OF CIRCULATING CARCINOEMBRYONIC ANTIGEN OF HUMAN DIGESTIVE SYSTEM
RADIOIMMUNOASSAY OF CIRCULATING CARCINOEMBRYONIC ANTIGEN OF HUMAN DIGESTIVE SYSTEM
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DOI：
10.1073/pnas.64.1.161
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发表时间：
1969-01-01
影响因子：
11.1
通讯作者：
GOLD, P
中科院分区：
文献类型：
--
作者：
THOMSON, DMP;KRUPEY, J;GOLD, P
本文报道了用放射免疫分析法测定结肠癌和直肠癌患者血清中消化系统癌胚抗原的含量。该测定法操作简单，具有高度的重现性和特异性。该测试检测到每毫升血清中含有2.5 ng癌胚抗原的浓度，这首次证明了癌症患者血清中存在循环肿瘤特异性抗原。
A radioimmunoassay has been developed for determining the serum levels of carcinoembryonic antigen of the human digestive system in patients with cancer of the colon and rectum. The assay is simple to perform and has a high degree of reproducibility and specificity. The test detects a concentration of 2.5 ng of carcinoembryonic antigen per ml of serum and this has provided the first demonstration of a circulating tumor-specific antigen in the sera of cancer patients.