Beneficial effects of early pulsed dye laser therapy in individuals with infantile hemangiomas.
Beneficial effects of early pulsed dye laser therapy in individuals with infantile hemangiomas.
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早期脉冲染料激光治疗对婴儿血管瘤患者的有益效果。
DOI：
10.1111/j.1524-4725.2012.02487.x
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发表时间：
2012
期刊：
影响因子：
--
通讯作者：
Friedlander,SheilaF
中科院分区：
文献类型：
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作者：
Admani,Shehla;Krakowski,AndrewC;Nelson,JohnS;Eichenfield,LawrenceF;Friedlander,SheilaF
婴儿血管瘤（IH）是一种良性血管生长，约占4%至5%的婴儿。1、2这些病变一般出现在出生后的最初几周，6 ~ 9个月迅速增殖，然后逐渐消失。3大多数IH病变随时间推移而消退，无功能或外观损害，但有一个重要的子集发生并发症，可能危及生命或永久性。4 IH的潜在并发症包括视觉或呼吸功能损害、溃疡、永久性解剖变形、色素沉着和严重瘢痕形成。Haggstrom和他的同事报告说，在国家登记处随访的1,058名IH患者中，有24%发生了并发症。最常见的累及区域是面部，22.9%的面部血管瘤发生并发症，43%需要干预。4 IH治疗的最佳方法包括根据位置和生长速度识别更可能有问题的病变，并及时进行干预，以预防或尽量减少不良后遗症。5 IH没有标准化的治疗策略，但各种治疗方法用于减少增殖期和增加退化速度。
Infantile hemangiomas (IH) are benign vascular growths seen in approximately 4% to 5% of infants. 1, 2 These lesions generally appear in the first few weeks of life, proliferate rapidly for 6 to 9 months, and then gradually involute. 3 Most IH lesions regress over time without functional or cosmetic impairment, but a significant subset develop complications that can be life threatening or permanent. 4Potential complications of IH include impairment of visual or respiratory function, ulceration, permanent anatomic distortion, dyspigmentation, and significant scarring. Haggstrom and colleagues reported that 24% of 1,058 patients with IH who were followed in a national registry developed complications. The most common area of involvement is the face, with 22.9% of facial hemangiomas developing complications and 43% requiring intervention. 4 The optimal approach to IH treatment consists of recognizing lesions that are more likely to be problematic based on location and rapidity of growth and intervening in a timely manner to prevent or minimize adverse sequelae. 5 There is no standardized management strategy for IH, but a variety of treatments are used to decrease the proliferative phase and increase speed of involution.