Dual Responsive Block Copolymer Micelles Functionalized by NIPAM and Azobenzene
Dual Responsive Block Copolymer Micelles Functionalized by NIPAM and Azobenzene
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NIPAM 和偶氮苯功能化的双响应嵌段共聚物胶束
DOI：
10.1002/marc.200900777
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发表时间：
2010-04-06
影响因子：
4.6
通讯作者：
Yu, Yanlei
中科院分区：
文献类型：
--
作者：
Feng, Ze;Lin, Li;Yu, Yanlei
采用ATRP合成了一种新型两亲性二嵌段共聚物，该共聚物由亲水性聚环氧乙烷嵌段和疏水性嵌段组成，由含偶氮苯的甲基丙烯酸酯和N-异丙基丙烯酰胺共聚而成。聚合物胶束表现出对热和光的双重响应。胶束的大小取决于温度，疏水核中的封装物质在加热和冷却过程中释放。胶束核心的疏水性表现为响应光的可逆变化，既没有破坏胶束，也没有包封物质泄漏，同时检测到偶氮苯部分的 H 聚集。
A novel amphiphilic diblock copolymer composed of a hydrophilic poly(ethylene oxide) block and a hydrophobic block copolymerized by azobenzene-containing methacrylate and N-isopropylacrylamide was synthesized using ATRP. The polymer micelles showed dual responsiveness to heat and light. The size of the micelles was dependent on temperature and the encapsulated substance in the hydrophobic cores was released during heating and cooling processes. The hydrophobicity of the micellar cores appeared as a reversible change in response to light with neither disruption of the micelles nor leakage of the encapsulated substance while H-aggregation of the azobenzene moieties was detected.