Enhancement of hydrogen peroxide production from an atmospheric pressure argon plasma jet and implications to the antibacterial activity of plasma activated water
Enhancement of hydrogen peroxide production from an atmospheric pressure argon plasma jet and implications to the antibacterial activity of plasma activated water
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DOI：
10.1088/1361-6595/abe0c9
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发表时间：
2021-03-01
影响因子：
3.8
通讯作者：
Short, Robert D.
中科院分区：
文献类型：
--
作者：
Ghimire, Bhagirath;Szili, Endre J.;Short, Robert D.
我们探讨如何配置氩气大气压等离子体射流，以提高其生产过氧化氢（H2 O2）在去离子水（DIW）。等离子体射流由内径为1.5 mm、外径为3 mm的石英管组成，该石英管具有上游内部针电极（在管内）和下游外部圆柱形电极（围绕管）。通过将氩气吹扫通过玻璃管并以10 kV（峰-峰）和23.5 kHz的频率向内部针电极施加正弦AC电压来操作等离子体。我们研究了以下操作参数对水中H_2O_2生成率的影响：管长、电极间距、接地电极与管口的距离、管口与DIW的距离、氩气流量和处理时间。通过研究等离子体射流的电学和光学性质，我们确定了上述操作参数如何影响主要的等离子体过程，这些过程通过电子诱导的解离反应和等离子体核心内和等离子体余辉中的UV光解促进H2 O2的产生;但需要注意的是，这些过程高度依赖于来自氩气供应和周围环境的水蒸气含量。然后，我们展示了如何在DIW中的等离子体诱导的低pH下H2 O2和其他等离子体产生的分子之间的协同作用在净化常见伤口病原体革兰氏阳性金黄色葡萄球菌和革兰氏阴性铜绿假单胞菌方面是非常有效的。本研究中提供的信息与医疗等离子体器械的设计相关，其中需要在生理上有用的浓度下产生等离子体反应物质（如H2 O2），以帮助实现该技术的全部临床潜力。
We explore how to configure an argon atmospheric-pressure plasma jet for enhancing its production of hydrogen peroxide (H2O2) in deionised water (DIW). The plasma jet consists of a quartz tube of 1.5 mm inner diameter and 3 mm outer diameter, with an upstream internal needle electrode (within the tube) and a downstream external cylindrical electrode (surrounding the tube). The plasma is operated by purging argon through the glass tube and applying a sinusoidal AC voltage to the internal needle electrode at 10 kV (peak-peak) with a frequency of 23.5 kHz. We study how the following operational parameters influence the production rate of H2O2 in water: tube length, inter-electrode separation distance, distance of the ground electrode from the tube orifice, distance between tube orifice and the DIW, argon flow rate and treatment time. By examining the electrical and optical properties of the plasma jet, we determine how the above operational parameters influence the major plasma processes that promote H2O2 generation through electron-induced dissociation reactions and UV photolysis within the plasma core and in the plasma afterglow; but with a caveat being that these processes are highly dependent on the water vapour content from the argon gas supply and ambient environment. We then demonstrate how the synergistic action between H2O2 and other plasma generated molecules at a plasma induced low pH in the DIW is highly effective at decontaminating common wound pathogens Gram-positive Staphylococus aureus and Gram-negative Pseudomonas aeruginosa. The information presented in this study is relevant in the design of medical plasma devices where production of plasma reactive species such as H2O2 at physiologically useful concentrations is needed to help realise the full clinical potential of the technology.