Demonstration of in vivo stability and lack of immunogenicity of a polyethyleneglycol-conjugated recombinant CHO-derived butyrylcholinesterase bioscavenger using a homologous macaque model.
Demonstration of in vivo stability and lack of immunogenicity of a polyethyleneglycol-conjugated recombinant CHO-derived butyrylcholinesterase bioscavenger using a homologous macaque model.
复制标题
使用同源猕猴模型证明聚乙二醇缀合的重组 CHO 衍生的丁酰胆碱酯酶生物清除剂的体内稳定性和缺乏免疫原性。
DOI:
10.1016/j.cbi.2010.02.042
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发表时间:
2010
影响因子:
5.1
通讯作者:
Lee,KeunmyoungD
中科院分区:
文献类型:
--
作者:
Rosenberg,YvonneJ;Saxena,Ashima;Sun,Wei;Jiang,Xiaoming;Chilukuri,Nageswararao;Luo,Chunjuan;Doctor,BhupendraP;Lee,KeunmyoungD