Inhibitory effect of reinioside C on vascular smooth muscle cells proliferation induced by angiotensin II via inhibiting NADPH oxidase-ROS-ENK1/2-NF-kappaB-AP-1 pathway.
Inhibitory effect of reinioside C on vascular smooth muscle cells proliferation induced by angiotensin II via inhibiting NADPH oxidase-ROS-ENK1/2-NF-kappaB-AP-1 pathway.
复制标题
瑞尼苷C通过抑制NADPH氧化酶-ROS-ENK1/2-NF-kappaB-AP-1途径对血管紧张素II诱导的血管平滑肌细胞增殖的抑制作用。
DOI：
--
复制
发表时间：
2014-09
期刊：
影响因子：
--
通讯作者：
Zhang GG
中科院分区：
文献类型：
--
作者：
Shi RZ;Tan GS;Hu CP;Zhang GG
血管紧张素II（angiotensin II，Ang II）诱导的血管平滑肌细胞（vascular smooth muscle cells，VSMCs）增殖在动脉粥样硬化和再狭窄的发病机制中起重要作用。本研究以远志的主要活性成分-瑞乃苷C为研究对象，
The proliferation of vascular smooth muscle cells (VSMCs) induced by angiotensin II (Ang II) plays a vital role in the pathogenesis of arteriosclerosis and restenosis. In the present study, the effect of reinioside C, a main active ingredient of Polygala