Carcinoma of the trachea. Clinicopathologic study of 41 cases
Carcinoma of the trachea. Clinicopathologic study of 41 cases
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气管癌。
DOI：
10.1002/1097-0142(197006)25:6
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发表时间：
1970
期刊：
影响因子：
6.2
通讯作者：
E. Beattie
中科院分区：
文献类型：
--
作者：
S. Hajdu;A. Huvos;J. Goodner;F. Foote;E. Beattie
在33年的时间里，41例原发性气管癌患者在纪念医院和詹姆斯尤因医院接受治疗。这些患者中有30例为表皮样癌，7例为腺样囊性癌，4例为粘液分泌腺癌。鉴于气管癌的隐匿性，对于有慢性咳嗽、咳血及胸部X线检查阴性的病人，在鉴别诊断时必须考虑到气管癌。气管癌的预后似乎主要取决于原发肿瘤的大小和组织学类型。表皮样腺癌和粘液分泌腺癌的预后似乎很严重。不到25%的表皮样癌患者存活一年或更长时间。然而，腺样囊性癌的预后要好得多。这些肿瘤有一个缓慢和阴险的过程，通常复发，并转移后几年的初步治疗。小的气管肿瘤可以通过内窥镜切除或部分切除气管来治疗。在广泛局限性疾病的情况下，手术和放疗的组合是治疗的选择。
During a period of 33 years, 41 patients with primary carcinoma of the trachea were treated at Memorial and James Ewing Hospitals. Thirty of these patients had epidermoid carcinoma, 7 had adenoid cystic carcinoma, and 4 had mucus‐secreting adenocarcinoma. In view of the cryptic symptomatology, tracheal carcinoma must be considered in the differential diagnosis in patients with chronic cough, hemoptysis, and negative chest roentgenogram. The prognosis of tracheal carcinoma appears to depend mainly upon size and histologic type of the primary tumor. The prognosis of epidermoid and mucus‐secreting adenocarcinoma appears to be grave. Less than 25 percent of the patients with epidermoid carcinoma survived one year or longer. Adenoid cystic carcinoma carried a much better prognosis, however. These tumors have a slow and insidious course, usually recur, and metastasize several years after initial treatment. Small tracheal tumors can be treated either by endoscopic excision or partial resection of the trachea. In the case of extensive localized disease, the combination of surgery and irradiation is the treatment of choice.