Electroconvulsive therapy for iatrogenic hypothalamic-hypopituitarism (CRF-ACTH type).
Electroconvulsive therapy for iatrogenic hypothalamic-hypopituitarism (CRF-ACTH type).
复制标题
医源性下丘脑垂体功能减退症（CRF-ACTH 型）的电休克治疗。
DOI：
10.1176/ajp.136.8.1074
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发表时间：
1979
影响因子：
17.7
通讯作者：
Patterson Cw
中科院分区：
文献类型：
--
作者：
Pitts Fn;Patterson Cw
：一名 41 岁男性，患有下丘脑垂体功能减退症（CRF-ACTH 型），在停用外源性地塞米松后持续 2 年，因严重慢性抑郁症接受双侧 ECT 治疗。在 17 次 ECT 疗程后，抑郁症仅短暂改善，但根据 2 年随访期间对四次美替拉酮压力测试的反应，下丘脑 - 垂体抑制完全且永久地清除。即使没有精神疾病，ECT 也可能是治疗持续性下丘脑垂体抑制的有效方法。
: A 41-year-old man with hypothalamic hypopituitarism (CRF-ACTH type) that persisted for 2 years after discontinuation of exogenous dexamethasone was treated with bilateral ECT for severe chronic depression. The depression improved only evanescently after 17 ECT sessions but the hypothalamic-pituitary suppression cleared completely and permanently, based on responses to four metyrapone stress tests in a 2-year follow-up period. ECT may be an effective treatment for persistent hypothalamic-pituitary suppression, even in the absence of a psychiatric disorder.