THE VIRULENCE AND IMMUNOGENICITY OF STRAINS DERIVED FROM SALMONELLA-TYPHOSA-58 (PANAMA CARRIER)
THE VIRULENCE AND IMMUNOGENICITY OF STRAINS DERIVED FROM SALMONELLA-TYPHOSA-58 (PANAMA CARRIER)
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DOI：
10.1084/jem.91.2.231
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发表时间：
1950-01-01
影响因子：
15.3
通讯作者：
BROWN, M
中科院分区：
文献类型：
--
作者：
BATSON, HC;LANDY, M;BROWN, M
本研究探讨了近缘链球菌强毒株和弱毒株疫苗的免疫原性。据报道，伤寒。没有证据表明所用菌株的毒力与其免疫原性之间存在任何本质关系，这是通过主动免疫小鼠保护试验以及人类的凝集素和小鼠保护性抗体反应确定的。
An investigation of the immunogenicity of vaccines prepared from closely related virulent and avirulent strains of S. typhosa is reported. No evidence was obtained of any essential relationship between the virulence of the strains employed and their immunogenicity, as determined by active-immunity mouse-protection tests and by the agglutinin and mouse-protective antibody response in human beings.