Prevalence and risk factors of strabismus in children and adolescents in South Korea: Korea National Health and Nutrition Examination Survey, 2008-2011.
Prevalence and risk factors of strabismus in children and adolescents in South Korea: Korea National Health and Nutrition Examination Survey, 2008-2011.
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DOI：
10.1371/journal.pone.0191857
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发表时间：
2018
期刊：
影响因子：
3.7
通讯作者：
Epidemiologic Survey Committee of the Korean Ophthalmological Society
中科院分区：
文献类型：
--
作者：
Han KE;Baek SH;Kim SH;Lim KH;Epidemiologic Survey Committee of the Korean Ophthalmological Society
评估韩国儿童和青少年水平斜视的患病率和危险因素。对2008年7月至2011年12月参加第四次和第五次韩国国家健康和营养检查调查（KNHANES IV-V）的5 935名5-18岁儿童和青少年进行了评价，并估计了水平斜视的患病率。进行单变量和多变量logistic回归分析，以确定人口统计学、社会经济学和临床风险因素与临床显著外斜视（≥15棱镜屈光度[PD]）和内斜视（≥10 PD）之间的相关性。在5，935例合格受试者中，84例受试者有临床显著的外斜视，13例有临床显著的内斜视。具有临床意义的水平斜视的总体患病率为1.6%（95%置信区间[CI]，1.2-2.1）：具有临床意义的外斜视为1.3%（95% CI，1.0-1.7），具有临床意义的内斜视为0.3%（95% CI，0.1-0.6）。具有临床意义的外斜视与弱视（校正比值比[aOR]，6.45; 95%CI，2.14-19.44）、斜视家族史（aOR，4.91; 95%CI，1.71-14.08）和散光≥1.0 D（aOR，1.84; 95%CI，1.13-2.98）相关。具有临床意义的内斜视与远视（aOR，12.16; 95%CI，1.31-113.04）和弱视（aOR，4.70; 95%CI，1.12-19.81）相关。其他人口统计学、社会经济学和临床变量与斜视无关。本研究提供了韩国儿童和青少年代表性人群中具有临床意义的外斜视和内斜视的患病率和独立风险因素的数据。
To evaluate the prevalence and risk factors associated with horizontal strabismus in children and adolescents in South Korea. A total of 5,935 children and adolescents 5–18 years of age who participated in the fourth and fifth Korean National Health and Nutrition Examination Survey (KNHANES IV-V) from July 2008 to December 2011 were evaluated and the prevalence of horizontal strabismus was estimated. Univariate and multivariate logistic regression analyses were conducted to determine the association between demographic, socioeconomic and clinical risk factors and clinically significant exodeviation (≥15 prism diopters [PD]) and esodeviation (≥10 PD). Among 5,935 eligible subjects, 84 subjects had clinically significant exodeviation and 13 had clinically significant esodeviation. The overall prevalence of clinically significant horizontal strabismus was 1.6% (95% confidence interval [CI], 1.2–2.1): 1.3% (95% CI, 1.0–1.7) for clinically significant exodeviation and 0.3% (95% CI, 0.1–0.6) for clinically significant esodeviation. Clinically significant exodeviation was associated with amblyopia (adjusted odds ratio [aOR], 6.45; 95% CI, 2.14–19.44), family history of strabismus (aOR, 4.91; 95% CI, 1.71–14.08) and astigmatism ≥1.0 D (aOR, 1.84; 95% CI, 1.13–2.98). Clinically significant esodeviation was associated with hyperopia (aOR, 12.16; 95% CI, 1.31–113.04) and amblyopia (aOR, 4.70; 95% CI, 1.12–19.81). Other demographic, socioeconomic, and clinical variables were not associated with strabismus. This study provides data on the prevalence and independent risk factors for clinically significant exodeviation and esodeviation in a representative population of children and adolescents in South Korea.