Development and characterization of a multidistance and multiwavelength diffuse correlation spectroscopy system.
Development and characterization of a multidistance and multiwavelength diffuse correlation spectroscopy system.
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DOI：
10.1117/1.nph.5.1.011015
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发表时间：
2018-01
期刊：
影响因子：
5.3
通讯作者：
Franceschini MA
中科院分区：
文献类型：
--
作者：
Tamborini D;Farzam P;Zimmermann B;Wu KC;Boas DA;Franceschini MA
This paper presents a multidistance and multiwavelength diffuse correlation spectroscopy (DCS) approach and its implementation to simultaneously measure the optical proprieties of deep tissue as well as the blood flow. The system consists of three long coherence length lasers at different wavelengths in the near-infrared, eight single-photon detectors, and a correlator board. With this approach, we collect both light intensity and DCS data at multiple distances and multiple wavelengths, which provide unique information to fit for all the parameters of interest: scattering, blood flow, and hemoglobin concentration. We present the characterization of the system and its validation with phantom measurements.
