PERMEABILITY OF BIOLOGICAL AND SYNTHETIC MOLECULES THROUGH DENTIN

PERMEABILITY OF BIOLOGICAL AND SYNTHETIC MOLECULES THROUGH DENTIN
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DOI:
10.1111/j.1365-2842.1994.tb01162.x
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发表时间:
1994-07-01
影响因子:
2.9
通讯作者:
FAT, JC
FAT, JC
中科院分区:
医学2区
文献类型:
--
作者:
HANKS, CT;WATAHA, JC;FAT, JC

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一些生物和合成分子,包括树脂和染料,通过牙本质的扩散,报告。体外测量是通过使用改进的“分裂室装置”的实验得出的。扩散被认为是间接成正比的牙本质厚度的所有分子。水溶性分子和乙醇溶性分子的渗透性与分子量成正比,除了荧光素,过氧化氢(H2 O2)和聚氨酯二甲基丙烯酸酯。所测试的树脂组分在水介质中的溶解度不足以在足以引起对牙髓细胞的细胞毒性的浓度下扩散通过0-5 mm牙本质。
The diffusion through dentine by a number of biological and synthetic molecules, including resins and dyes, is reported. In vitro measurements were derived by experiments with a modified 'split-chamber device'. Diffusion was found to be indirectly proportional to dentine thickness for all molecules. Permeability of water-soluble molecules and ethanol-soluble molecules was proportional to the molecular weights, except for fluorescein, hydrogen peroxide (H2O2) and urethane dimethacrylate. The resin components tested are not soluble enough in an aqueous medium to diffuse through 0-5 mm dentine at sufficient concentrations to cause cytotoxicity to pulpal cells.