900-MHz Microwave Radiation Enhances -Ray Adverse Effects on SHG44 Cells
900-MHz Microwave Radiation Enhances -Ray Adverse Effects on SHG44 Cells
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DOI：
10.1080/15287390902841466
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发表时间：
2009-01-01
影响因子：
2.6
通讯作者：
Tong, Jian
中科院分区：
文献类型：
--
作者：
Cao, Yi;Zhang, Wei;Tong, Jian
手机在全球范围内被广泛使用。然而，由于暴露在移动电话产生的电磁场(EMF)中而产生的生物效应在很大程度上是未知的。人类在环境和职业中对射线的暴露是一种与生物相关的现象。因此，开展了研究，以检查射线和电磁场之间的相互作用对人类健康的影响。在这项研究中，暴露在900兆赫电磁场扩展射线对SHG44细胞的损伤。暴露前电磁场可增强射线照射对细胞增殖的抑制作用和细胞凋亡率。电磁场和射线照射通过触发应激反应而产生协同效应，增加了细胞内的氧自由基，但HSP70在mRNA和蛋白质水平的表达没有改变。数据表明，电磁场增强了射线对细胞功能的不利影响。
Mobile phones are widely used globally. However, the biological effects due to exposure to electromagnetic fields (EMF) produced by mobile phones are largely unknown. Environmental and occupational exposure of humans to -rays is a biologically relevant phenomenon. Consequently studies were undertaken to examine the interactions between -rays and EMF on human health. In this study, exposure to 900-MHz EMF expanded -ray damage to SHG44 cells. Preexposure EMF enhanced the decrease in cell proliferation induced by -ray irradiation and the rate of apoptosis. The combination of EMF and -ray exposure resulted in a synergistic effect by triggering stress response, which increased reactive oxygen species, but the expression of hsp70 at both mRNA and protein levels remained unaltered. Data indicate that the adverse effects of -rays on cellular functions are strengthened by EMF.